The mission of my research program is to design supramolecular peptide and peptidomimetic biomaterials and elucidate their mechanisms of interaction with immune cells for application as cell-free vaccines. My research program has three primary focus areas:
- Develop multifactorial and rationally designed vaccines and immunotherapies based on supramolecular nanomaterials for modulating the immune system in health and disease.
- Elucidate the effects of chirality on molecular self-assembly and innate immunity to fabricate mirror-image nanomaterials for immuno/biomedical applications.
- Pioneer the use of supramolecular scaffolds for the assembly of signalosomes for amplification and spatiotemporal regulation of immune signaling.